Geoffrey L Smith Selected Research

Nuclear Proteins (Protein, Nuclear)

9/2013

Vaccinia virus protein N2 is a nuclear IRF3 inhibitor that promotes virulence.

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Geoffrey L Smith Research Topics

Disease

62	Infections 03/2024 - 05/2001
19	Smallpox (Variola) 03/2024 - 02/2003
17	Virus Diseases (Viral Diseases) 01/2022 - 12/2003
6	Vaccinia 12/2023 - 04/2005
5	Poxviridae Infections 01/2023 - 04/2005
4	Inflammation (Inflammations) 10/2022 - 09/2003
4	B-Cell Lymphoma (Lymphoma, B Cell) 03/2015 - 12/2011
3	COVID-19 01/2023 - 01/2022
3	Communicable Diseases (Infectious Diseases) 01/2019 - 05/2013
3	Porcine Reproductive and Respiratory Syndrome (PRRS) 11/2018 - 09/2011
2	Mpox (monkeypox) 03/2024 - 02/2024
2	Disease Progression 01/2022 - 10/2017
2	RNA Virus Infections 01/2022 - 12/2012
2	Neoplasms (Cancer) 01/2017 - 01/2014
2	Hypoxia (Hypoxemia) 02/2015 - 07/2013
2	Malaria 05/2013 - 06/2003
1	Cowpox 03/2024
1	Acquired Immunodeficiency Syndrome (AIDS) 05/2013
1	DNA Virus Infections 01/2013
1	Severe Combined Immunodeficiency (Bare Lymphocyte Syndrome) 12/2012
1	Bites and Stings (Sting) 12/2012
1	Superinfection 09/2012
1	Rupture 07/2009

Drug/Important Bio-Agent (IBA)

50	Proteins (Proteins, Gene)FDA Link 03/2024 - 09/2001
14	VaccinesIBA 02/2024 - 01/2006
11	InterferonsIBA 01/2022 - 03/2002
10	Antiviral Agents (Antivirals)IBA 03/2024 - 02/2003
7	ChemokinesIBA 01/2022 - 02/2003
7	CytokinesIBA 01/2022 - 09/2007
7	Glycoproteins (Glycoprotein)IBA 01/2018 - 09/2001
6	Transcription Factors (Transcription Factor)IBA 10/2022 - 12/2011
5	Pattern Recognition ReceptorsIBA 11/2018 - 09/2011
5	Virulence Factors (Pathogenicity Factors)IBA 07/2013 - 06/2007
4	AntigensIBA 01/2023 - 06/2003
4	Interferon Type IIBA 01/2022 - 12/2012
4	DNA (Deoxyribonucleic Acid)IBA 11/2018 - 06/2003
3	Viral ProteinsIBA 12/2023 - 12/2016
3	Immunologic Factors (Immunomodulators)IBA 11/2022 - 09/2013
3	Phosphotransferases (Kinase)IBA 01/2022 - 12/2012
3	Amino Acids FDA Link 01/2022 - 12/2003
3	Nucleic AcidsIBA 11/2018 - 12/2012
3	Peptides (Polypeptides)IBA 09/2015 - 10/2008
3	Carrier Proteins (Binding Protein)IBA 06/2007 - 02/2003
2	Interferon Regulatory Factor-3 (Interferon Regulatory Factor 3)IBA 03/2024 - 12/2012
2	ProteomeIBA 12/2023 - 10/2008
2	LigandsIBA 01/2022 - 08/2003
2	RNA (Ribonucleic Acid)IBA 01/2022 - 12/2012
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2022 - 09/2007
2	Apoptosis Regulatory ProteinsIBA 01/2017 - 12/2014
2	Oxygen (Dioxygen)IBA 02/2015 - 07/2013
2	lysyl- arginyl- alanyl- lysyl- alanyl- lysyl- threonyl- threonyl- lysyl- lysyl- arginine (PKCS)IBA 01/2013 - 12/2012
2	polyanionsIBA 07/2009 - 04/2006
2	Interferon LambdaIBA 06/2007 - 06/2005
2	CCR8 ReceptorsIBA 04/2006 - 12/2003
2	AntibodiesIBA 11/2005 - 04/2005
2	CC ChemokinesIBA 08/2003 - 02/2003
1	InflammasomesIBA 12/2023
1	3- (2- methoxyphenyl)- 5- methoxy- 1,3,4- oxadiazol- 2(3H)- oneIBA 12/2023
1	Peptidyl-Dipeptidase A (Angiotensin Converting Enzyme)IBA 01/2023
1	SARS-CoV-2 spike proteinIBA 01/2023
1	ChAdOx1 nCoV-19IBA 01/2023
1	EphrinsIBA 01/2022
1	ProtocadherinsIBA 01/2022
1	Anti-Bacterial Agents (Antibiotics)IBA 01/2022
1	Membrane Proteins (Integral Membrane Proteins)IBA 01/2022
1	T-Cell Antigen Receptors (T-Cell Receptor)IBA 01/2022
1	Viral RNAIBA 01/2022
1	HLA-C Antigens (HLA-C)IBA 01/2022
1	Cytokine Receptors (Cytokine Receptor)IBA 01/2022
1	Small Interfering RNA (siRNA)IBA 01/2022
1	Viral VaccinesIBA 01/2020
1	Prednisolone (Predate)FDA LinkGeneric 01/2020
1	Histone Deacetylases (Histone Deacetylase)IBA 01/2019
1	CateninsIBA 12/2017
1	AntioxidantsIBA 10/2017
1	Calcium Channels (Calcium Channel)IBA 01/2017
1	Phosphoric Monoester Hydrolases (Phosphatases)IBA 12/2016
1	Mitogen-Activated Protein KinasesIBA 01/2016
1	Transcription Factor AP-1 (Transcription Factor AP 1)IBA 01/2016
1	Glutamine (L-Glutamine)FDA Link 02/2015
1	NucleotidesIBA 02/2015
1	Caspase 3 (Caspase-3)IBA 12/2014
1	UbiquitinIBA 09/2014
1	Interferon Regulatory FactorsIBA 09/2013
1	Nuclear Proteins (Protein, Nuclear)IBA 09/2013
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 07/2013
1	Pyruvic Acid (Pyruvate)IBA 07/2013
1	Glucose (Dextrose)FDA LinkGeneric 07/2013
1	Oxidoreductases (Dehydrogenase)IBA 07/2013
1	DNA-Activated Protein KinaseIBA 01/2013
1	Pathogen-Associated Molecular Pattern MoleculesIBA 01/2013
1	Protein SIBA 09/2012
1	Smallpox Vaccine (Vaccine, Smallpox)FDA Link 10/2011
1	CaspasesIBA 05/2010
1	Peptide Hydrolases (Proteases)FDA Link 05/2010
1	KinesinsIBA 02/2010
1	polycationsIBA 07/2009
1	Janus Kinase 2IBA 04/2009
1	STAT1 Transcription FactorIBA 04/2009

Therapy/Procedure

2	Therapeutics 01/2023 - 10/2017